During a job interview, have you ever been asked to piss for your new employer? New applicants for many of the Fortune 500 corporations are now being forced to take a drug test. In fact, 15 million will be tested this year. Drug byproducts can be detected in urine, blood, hair, external residue, and even perspiration! Drugs aren’t the only things they test for; employers are using urinalysis to test women for pregnancy. Pregnant women are getting laid off or denied employment after taking such a test. Parents are spying on their children. The DOD Directive requires the military to screen all active duty members annually. If you don’t want to be a victim of the drug war, this text will help you. If you are well known, this text may protect your reputation. I strongly recommended that drug users pot smokers in particular read this.

Detection times vary depending on analytical method used, drug metabolism, tolerance, patient’s condition, fluid intake and method and frequency of ingestion.

Other factors determining degree of intoxication include metabolism, tolerance, frequency of intake, fluid intake, amount of marijuana, potency of marijuana, and length of time you’ve been a user. If you use marijuana on rare occasions, your urine may be clean of metabolites in less than a week. There is a common and strange phenomena that occurs with chronic users. You would expect a chronic user to have the longest detection time and the smallest chance of passing. This is not always the case. A chronic user with a high tolerance will eliminate drugs quicker than an occasional user. Chronic users have tested negative after a week long binge. Lipid tissue also makes a huge difference. Skinny users not only have a faster metabolism usually, but also lack storage for THC metabolites. Fat will cause a lag in excretion pattern, and lead to a longer detection time. You should now be able to understand why an individuals detection time for THC is so unpredictable.

Positive defined 50 nanograms of THC metabolites per milliliter defines a “presumptive positive” by NIDA certified labs. This value was originally 20 ngmL, but too many false positives resulted. So the level was raised to 100 ngmL to reduce false positives. As of January 1995, the threshold was lowered back down to 50 ngmL because drinking water would easily bring a positive below 100 ng. Be aware that these cutoffs are not universally consistent.

Drink at least eight hefty glasses of fluid preferably water just prior to the test. Many people start drinking water several days before the test; which is useless. Water does NOT clean any THC metabolites out of your system because THC is not water soluble. Water only dilutes urine temporarily. Do not over do it; you can get water intoxication. People can actually overdose and even die from water intoxication. It’s very hard to do, and you’ll vomit before anything gets serious.

Eating red meat will boost creatinine levels. If you eat a lot of red meat for the 3 days prior to the test, your creatinine level will be normal, and the lab won’t know that you’ve diluted your urine sample.

If you are a regular user of prescription medications, you know that these drugs can be costly to purchase. Cutting back on drugs can be dangerous to your health, but if you are on a fixed income your choices can seem limited. Lets look at some cost effective ways for you to slash your prescription costs.

1. Go generic. Many medications prescribed are for name brand drugs. Ask your doctor if he or she can substitute a generic drug which can lower your costs significantly.

2. Split the pill. If you have been prescribed 40 mg of a drug and only need 20 mg consider investing in a pill splitter. You can reduce your costs significantly especially if the price difference between the two strengths is minimal; check with your pharmacist to make sure that the drug will not lose effectiveness if it is split.

3. Shop in Canada. Regulated pharmacies based in Canada tout their lower prescription costs to American consumers via the internet. Not all drugs are lower, especially when including shipping and handling cost, however.

4. Assistance programs. Many pharmaceutical companies offer drug assistance programs for users of their products. Contact the maker of your medication directly for assistance.

5. Go big. Purchasing a two month supply can be much more cost effective than purchasing a one month supply. Check to see if your insurance company permits this practice.

6. Shop around. Compare prices between pharmacies including online providers.

7. Government assistance. You may be eligible for special assistance through government programs such as Medicare and Medicaid.

8. Coupons. Occasionally, companies give away free samples of their products or will give you money saving coupons. Check with your doctor about getting free samples too.

You can save money on prescription drugs with a little bit of pluck and with plenty of determination. Shop wisely and you will be certain to save money in this day of ever spiraling health costs.

Many Americans feel that Marijuana is helping fund the war on terror, but making a war on drugs and keeping Marijuana illegal has not stopped millions of Americans from smoking pot everyday. So what is the answer?

First, why is Marijuana illegal? In the 1930′s William Randolph Hearst, who had significant financial interests in the timber industry testified to congress on the evils of marijuana, saying things like it make people insane and commit acts of cannibalism? at this time very few even knew what it was and to stop people from going insane Congress decided to make it illegal.

The truth is many paper manufacturers were thinking of changing from using trees to make paper to using hemp because it was cheaper and easier to grow and better for the environment, and Hearst stood to loose millions so he used his influence and testimony to help get marijuana banned in the USA.

So now that we know why it was made illegal, we can realize that not only would making it legal in the United States stop terrorist from smuggling it into the USA, but would give us another option to cutting down of millions of trees every year for paper products that can be made better from hemp.

Hemp has thousands of uses that we are unable to exploit because of its illegal status.

During WWII hemp was used for the rigging on parachutes as well as rope and material for uniforms.

Nowadays Marijuana can be used to relieve pain and some of the effect of cancer treatments and old age.

It has been proven to slow down the spreading of Alzheimer’s, relieve the pressure behind the eyes from glaucoma. It also helps relieve migraine headaches and the side effect of cancer treatment.

But until the United States realizes how much money can be made from legalizing it, it will remain illegal.

This is much like the situation with online casinos in the USA. America was sending billions of dollars out of the country and the government needed to do something to keep the money here, so they banned and just like online casinos and online gambling I believe one day the government will learn to take advantage of these things instead of just banning them.

Eventually the USA will realize that the best way to stop the flow of money out of the country is not to ban marijuana or online casinos, but to enter the market and compete.

If the USA did what Amsterdam has done the government would make not only billions in Taxes from the sales of Marijuana, but the economy would boom from all the tourism that it would bring in from all over the world.

The truth of the matter is that legalization is inevitable. The attitude of people has changed so drastically over the last 30 years, that eventually when the younger generations start to take over marijuana will eventually become legal because they understand the truth, and that is banning something only makes the market for it stronger.

Hunting for Genetic Mutations and Cancer
The current paradigm in medical research holds that the cause of most cancers is a genetic mutation. For instance, according to the National Human Genome Research Institute NHGRI, an institute at the NIH, “all cancers are based on genetic mutations in body cells.” In fact, mutation hunting is big business. Just look at the NIH budget allocated to discoveries of genetic mutations, the number of biotech companies chasing genetic mutations, the magnitude of the licensing agreements between biotech and pharmaceutical companies aimed to utilize newly discovered genetic mutations, and the number of stories in the media on genetic mutations and their so-called “link” to disease. However, this huge effort and billions of dollars has produced few discoveries and little benefits to the public. The reason for this limited success is simple. The cause of cancer is not a genetic mutation.

The story of the BRCA1 gene is a typical example of mutation hunting.

The Mystery of BRCA1
Genes, in general, produce proteins, which are the building blocks of cells. The concentration of the protein is tightly regulated. A mutated gene produces an abnormal concentration of its protein, which may lead to disease. In 1994, Mark Skolnick, PhD, discovered the BRCA1 gene BRCA1 is short for BReast CAncer 1. Following the discovery, scientists observed an abnormally low level of the BRCA1 protein in breast cancer tissues. The BRCA1 protein is a cell cycle suppressor, which means that the protein prevents cell replication. This observation created a lot of excitement. At the time, scientists believed that they were on the verge of finding the cause of breast cancer. The reasoning was that breast cancer patients must have a mutated BRCA1 gene, which would explain the decreased production of the protein, and the excessive replication of breast cancer cells in tumors.

In the United States, 180,000 cases of breast cancer are diagnosed each year. However, the BRCA1 gene is mutated in less than 5 of these cases. In more than 95 of breast cancer patients the gene is not mutated.

So here is the mystery. If the gene is not mutated in the great majority of the breast cancer patients, why are the tumors showing low levels of the BRCA1 protein? Today, this is one of the biggest mysteries in cancer research.

The BRCA1 gene is not unique. Many normal non-mutated genes exhibit a mysterious abnormal increased or decreased production of proteins in cancer. Moreover, studies also report abnormal gene expression of normal genes in other diseases, such as atherosclerosis, obesity, osteoarthritis, type II diabetes, alopecia, type I diabetes, multiple sclerosis, asthma, lupus, thyroiditis, inflammatory bowel disease, rheumatoid arthritis, psoriasis, atopic dermatitis, and graft versus host disease.

The Discovery
A virus is a collection of genes. To replicate, some viruses settle in the nucleus of the host cell and use the cell machinery to replicate. What is the effect of a viral gene on the production of cellular proteins?

Think of a gene as an assembly line of a protein. Like all assembly lines, the gene has two parts, a conveyor the gene coding section, and a control panel the gene promoterenhancer. Imagine a cellular shop that assembles a product called BRCA1. One of the many buttons on the control panel is called N-box. Pressing the button increases production. However, only a small number of operators called transcription factors, those who pass a special certification called the p300 test, have permission to press this button. What happens when a virus opens a shop across the street from the cellular shop called latent infection to produce its viral products? The control panel in the viral shop also has an N-box button. To start production, the virus begins to hire away some of the certified operators. What is the effect of this “hiring away” on the number of available BRCA1 units? The number decreases. Moreover, the decrease becomes apparent even before the virus starts production the “hiring away” is what creates the effect, not the viral proteins. The viral assembly line competes with the BRCA1 assembly line for the certified operators, and by hiring them away prevents the cellular shop from producing the optimum, or “healthy” number of BRCA1 units. The lower number of BRCA1 units leads to excessive cell replication and breast cancer. See a more technical description in a recent paper published in the European Journal of Cancer.

The infection with the latent virus causes abnormal production of other genes, and as a result, the development of other chronic diseases. This sequence of events easily explains why people who suffer from obesity are also more likely to suffer from diabetes, cancer, and heart disease, and why a recent large scale study found that a low-fat diet does not protect against breast cancer. It also explains another surprising observation that male pattern baldness is associated with heart disease and prostate cancer. In general, this sequence of events easily explains the numerous observations indicating a co-existence or co-morbidity of some chronic diseases.

This discovery was first described by Dr. Hanan Polansky in his book, Microcompetition with Foreign DNA and the Origin of Chronic Disease, published by The Center for the Biology of Chronic Disease.

To summarize the cause of cancer, and other chronic diseases, is not a genetic mutation, it’s an infection with a latent virus.

Reaction of the Scientific Community
What is the scientific community saying about Dr. Polansky’s discovery?

Consider what the famous heart surgeon and “Living Legend,” Michael E. DeBakey, said about the discovery, “The theory underlying the basic concept concerning the origin of chronic diseases presented by Dr. Polansky is most interesting, indeed fascinating Perhaps a symposium could be held to provide a forum for further discussions and critiques of this fascinating theory.”

Elena N. Naumova, PhD, Associate Professor, Department of Family Medicine and Community Health, Tufts University School of Medicine, said, “Dr. Polansky’s work compellingly demonstrates a framework that could bring together researchers from different fields. His proposed theory will work its magic by clarifying ambiguous definitions, identifying similarities and differences in various biological processes, and discovering new pathways I believe that Dr. Polansky’s book will catalyze the scientific learning process, promote interdisciplinary cross-fertilization, stimulate development of treatment strategies and drug discovery, and leave the reader inspired.”

Sivasubramanian Baskar, PhD, Senior Scientist from the National Cancer Institute, NIH, said, “At first, I wish to congratulate Dr. Hanan Polansky for his scientific bravery to take such a unique, novel approach to further stimulate our understanding of the origin and establishment of chronic diseases. The philosophy underscored is an excellent one … The amazing correlation between theoretical predictions and observed in vivo effects seems to bring us a step closer to a deeper understanding of such complex biologic processes.”

Marc Pouliot, PhD, Assistant Professor, Department of Anatomy and Physiology, Faculty of Medicine, Universit Laval, Canada, said, “The concept of microcompetition will change our approach in the study of chronic diseases and will furthermore give scientists a higher level of understanding in biology. Presentation of this concept undoubtedly provides a new set of opportunities for attacking chronic diseases They lead the way to new approaches in chronic disease treatment.”

Howard A. Young, PhD, Section Head, Cellular and Molecular Immunology Section, Laboratory of Experimental Immunology, National Cancer Institute, NIH, said, “In summary, Dr. Polansky is to be applauded for his attempt to provide a unifying basis for chronic diseases. His theories are stimulating and offer a basis for experimental testing and possible treatment.”

Michael J. Gonzalez, PhD, Professor, Medical Sciences, University of Puerto Rico, said, “I know this book will profoundly impact medical research, drug discovery, as well as natural therapies. I also believe it will benefit the scientific community and society in general by providing further means of treatment for conditions in which only palliative care is available.”

You can find more reactions and the biographies the scientists reacting to Dr. Polansky’s discovery on the publisher’s see link below.

Hope for Cure and Protection
The significance of Dr. Polansky’s discovery cannot be overstated. For the first time, we can start to feel a little better about these diseases. With his discovery, pharmaceutical and biotech companies can now start to design medications that will target the cause of the disease rather than its symptoms, and therefore, cure the sick and protect the healthy from these deadly diseases.

Ketamine is a drug for use in human and veterinary medicine developed by Parke-Davis today a part of Pfizer in 1962. Ketamine is used to manage pain among large animals, though it has less effect on bovines. Ketamine is a dissociative anesthetic developed in 1963 to replace PCP and currently used in human anesthesia and veterinary medicine. Ketamine is relatively safe when used in hospitals. Ketamine is often used at all-night dance parties raves, nightclubs, and concerts. Ketamine is a liquid, but most users let it evaporate into a white powder, then snort it. Ketamine is an anaesthetic that is available only to physicians and is “scheduled” in several states. Ketamine is known to cause hallucinations, nausea, mental clouding, loss of memory and an amnestic feeling may occur. Ketamine is unusual among injectable drugs since it is injected both intravenously and intramuscularly. Ketamine is a depressant at higher doses and can dangerously reduce heart rate and respiratory function. Now that Ketamine is federally illegal, it is expected that most states will also eventually schedule it. The majority of fatalities occur when ketamine is combined with other CNS depressants like alcohol, benzodiazepines and a mixture of other illicit drugs. The most frequent and sometimes only way to obtain ketamine is through the diversion or theft of legal pharmaceuticals.

An allergic asthma. It is a chronic inflammatory disorder of the lung airways. It’s symptoms are made worse by exposure to an allergen e.g., dust, mold, pollen, dust mite allergens and animal dander to which the patient has been sensitized.

A simple sneeze could trigger allergic asthma or a simple cough could lead to that as well.

What are the symptoms of allergic asthma?

The symptoms of allergic and non-allergic asthma are the same. They include coughing, wheezing, shortness of breath or rapid breathing, and chest tightness. These symptoms are often provoked by an identifiable trigger.

What factors can cause or trigger allergic asthma?

A family history of allergies is the most important predictor of whether a person will develop asthma. Environmental substances allergens can trigger an exacerbation – or attack – in patients with allergic asthma.

The allergens include tree, grass, and weed pollen, plus molds, animal dander, dust mites and cockroach droppings. Asthma attacks can also be triggered by viral infections, exercise, cold air and non-specific irritants.

How many people suffer from allergic asthma?

Allergic asthma is the most common form of asthma. According to the National Institute of Environmental Health Sciences, of the 17 million asthma sufferers in the United States, 10 million approximately 60 percent have allergic asthma. Three million are children and 7 million are adults.

What is the relationship between allergies and allergic asthma?

Most people with asthma also suffer from other allergic disorders. In fact, research from the World Health Organization WHO shows that at least 70 percent of asthmatics also suffer from allergic rhinitis or “hay fever.”

Nasal allergies and allergic asthma are both triggered by exposure to allergens, initiating a series of events that result in tightening of the airways, swelling of the lining of the airways, nose and eyes, and mucus production.

What is IgE and why is it important in allergic asthma?

IgE Immunoglobulin E is an antibody in the human immune system that plays a critical role in the allergic process.

When an individual is sensitized to an allergen, he or she produces an IgE antibody directed against that allergen. The IgE antibody attaches to mast cells.

When the individual is exposed to that same allergen again, the allergen binds to the IgE on the mast cell causing it to release substances such as histamine, prostaglandins and leukotrienes, which cause symptoms such as chest tightness, coughing and wheezing.

What treatments are available for people suffering from allergic asthma?

It is important for people with asthma to seek treatment. First, patients are evaluated to identify their specific allergic triggers and a program of allergen avoidance is recommended.

Asthma is treated with medications including anti-inflammatory agents, such as corticosteroids and anti-leukotrienes that decrease inflammation in the lungs, and bronchodilators used for relief of symptoms.

Allergen immunotherapy, also known as allergy shots, is a program of injections that reduces allergic sensitization.

A new drug currently under review by the Food and Drug Administration FDA, known as anti-IgE, concentrates on short-circuiting the allergic reaction in the body before it even begins.

Anti-IgE therapy stops the allergic reaction before it starts, allowing the patient to avoid allergy symptoms that often trigger an asthma attack or lead to the development of asthma attacks.

Researchers are looking for targets for new forms of treatment. Future therapies may focus on cytokines, substances that maintain the chronic inflammation responsible for asthma.

Other research may also lead to the development of new anti-inflammatory drugs, which may retain the anti-inflammatory effects of corticosteroids but cause fewer systemic side effects.

As the more and more developing countries are emerging, more and more air pollution is arising, whether asthma or allergic asthma, the number of people having is rising.

They could have acquired this chronic illness rather than having it genetically as the environment is getting more and more dirtier.